1. [ noun ] (transportation,geography) street that serves as a principal thoroughfare for traffic
Synonyms: high_street
Related terms: street main_drag
2. [ noun ] (government,geography) any small town (or the people who inhabit it); generally used to represent parochialism and materialism (after a novel by Sinclair Lewis)

"Main Street will never vote for a liberal politician"

Related terms: town
Similar spelling:   mainsheet