fastidious
1. [ adjective ] giving and careful attention to detail; hard to please; excessively concerned with cleanliness
Examples:

"a fastidious and incisive intellect" "fastidious about personal cleanliness"

Related terms: unfastidious finical choosy dainty pernickety meticulous old-maidish meticulous refined tidy
2. [ adjective ] (microbiology) having complicated nutritional requirements; especially growing only in special artificial cultures
Synonyms: exacting
Examples:

"fastidious microorganisms" "certain highly specialized xerophytes are extremely exacting in their requirements"

Related terms: unfastidious microbiology
Similar spelling:   fastidiously
  factitious
  factoid