1. [ noun ] a state in which everything seems wrong and will turn out badly
Synonyms: desperation

"they were rescued from despair at the last minute"

Related terms: condition
2. [ noun ] the feeling that everything is wrong and nothing will turn out well
Related terms: hope feeling discouragement pessimism resignation hopelessness
3. [ verb ] abandon hope; give up hope; lose heart

"Don't despair--help is on the way!"

Related terms: hope despond
Similar spelling:   despairing